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Article

Selective pressures of human immunodeficiency virus type 1 (HIV-1) during pediatric infection.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2007

Leal Elcio, Janini Mario, Diaz Ricardo S

Abstract excerpt

Pediatric HIV-1 infection presents remarkable features that are distinct from those observed in adult infection. In vertically HIV-1-infected children, the viral load declines more slowly, and the cytotoxic T-lymphocyte response emerges late, only after the sixth month of life. This response generally tends to be narrow and less intense than that seen in adults. While the nuances of immune response at the...

Topics

Adult
Age Factors
Child
Child, Preschool
Codon
Female
Gene Products, env
Genes, Viral
Genetic Variation
HIV Infections
HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Infant

Infant, Newborn

Phylogeny

Source

Identifiers

PMID: 17719854
DOI: 10.1016/j.meegid.2007.07.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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