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Article

Impact of Clinical Parameters in the Intrahost Evolution of HIV-1 Subtype B in Pediatric Patients: A Machine Learning Approach.

Genome biology and evolution - 1 Oct 2017

Rojas Sánchez Patricia, Cobos Alberto, Navaro Marisa, Ramos José Tomas, Pagán Israel, Holguín África

Abstract excerpt

Determining the factors modulating the genetic diversity of HIV-1 populations is essential to understand viral evolution. This study analyzes the relative importance of clinical factors in the intrahost HIV-1 subtype B (HIV-1B) evolution and in the fixation of drug resistance mutations (DRM) during longitudinal pediatric HIV-1 infection. We recovered 162 partial HIV-1B pol sequences (from 3 to 24 per patient)...

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Identifiers

PMID: 29044435
DOI: 10.1093/gbe/evx193
PMCID: PMC5647794

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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