Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[The role of lamins and mutations of LMNA gene in physiological and premature aging].

Postepy biochemii - 1 Jan 2007

Sliwińska Małgorzata Alicja

Abstract excerpt

Lamins belong to type V intermediate filaments superfamily. They are the main structural constituencies of the nuclear lamina but they also influence on chromatin structure, regulation of gene expression, localization and probably protein degradation. Because lamins play many different roles within the cell, mutations in their genes can results in variety of pathological phenotypes. Mutations in LMNA gene are the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Aging, Premature
Share to Alternative Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lamin Type A

Share to Lamins

Share to Nuclear Envelope

Share to Progeria

Share to Protein Isoforms

Source

Identifiers

PMID: 17718387

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[The role of lamins and mutations of LMNA gene in physiological and premature aging].PMID 17718387Read ↗

Hutchinson-Gilford Progeria Syndrome: An Overview of the Molecular Mechanism, Pathophysiology and Therapeutic Approach.Semantic proximity Read ↗

Towards delineating the chain of events that cause premature senescence in the accelerated aging syndrome Hutchinson-Gilford progeria (HGPS).Semantic proximity Read ↗

[Laminopathies: lipodystrophies, insulin resistance, syndromes of accelerated ageing... and others].Semantic proximity Read ↗

Premature aging syndromes: From patients to mechanism.Semantic proximity Read ↗

[Laminopathies: one gene, several diseases].Semantic proximity Read ↗

Evidence for the involvement of lamins in aging.Semantic proximity Read ↗

Molecular insights into the premature aging disease progeria.Semantic proximity Read ↗

Recent advances in understanding the role of lamins in health and diseaseSemantic proximity Read ↗

Hutchinson-Gilford Progeria Syndrome: A premature aging disease caused by LMNA gene mutations.Semantic proximity Read ↗

Hutchinson-Gilford Progeria Syndrome: A Premature Aging Disease.Semantic proximity Read ↗

Hutchinson-Gilford progeria syndrome.Semantic proximity Read ↗

Nuclear lamins, diseases and aging.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.