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Article

Hutchinson-Gilford Progeria Syndrome: An Overview of the Molecular Mechanism, Pathophysiology and Therapeutic Approach.

Current gene therapy - 1 Jan 2021

Rahman Md Mominur, Ferdous Kazi Sayma, Ahmed Muniruddin, Islam Mohammad Touhidul, Khan Md Robin, Perveen Asma, Ashraf Ghulam Md, Uddin Md Sahab

Abstract excerpt

Lamin A/C encoded by the LMNA gene is an essential component for maintaining the nuclear structure. Mutation in the lamin A/C leads to a group of inherited disorders is known as laminopathies. In the human body, there are several mutations in the LMNA gene that have been identified. It can affect diverse organs or tissues or can be systemic, causing different diseases. In this review, we mainly focused on one of...

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Identifiers

PMID: 33655857
DOI: 10.2174/1566523221666210303100805

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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