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Article

Nuclear lamins, diseases and aging.

Current opinion in cell biology - 1 Jun 2006

Mattout Anna, Dechat Thomas, Adam Stephen A, Goldman Robert D, Gruenbaum Yosef

Abstract excerpt

Nuclear lamins are type V intermediate filament proteins. They are the major building blocks of the peripheral nuclear lamina, a complex meshwork of proteins underlying the inner nuclear membrane. In addition to providing nuclear shape and mechanical stability, they are required for chromatin organization, transcription regulation, DNA replication, nuclear assembly and nuclear positioning. Over the past few...

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Identifiers

PMID: 16632339
DOI: 10.1016/j.ceb.2006.03.007

Genes

LMNA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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