[Clinical molecular genetics for PARK8 (LRRK2)].

Article

[Clinical molecular genetics for PARK8 (LRRK2)].

Brain and nerve = Shinkei kenkyu no shinpo - 1 Aug 2007

Tomiyama Hiroyuki, Hatano Taku, Hattori Nobutaka

Abstract excerpt

Parkinson's disease (PD) is an etiologically heterogeneous disorder characterized by parkinsonism (bradykinesia, resting tremor, rigidity, and postural instability) with good response to L-dopa. PD is the second most prevalent neurodegenerative disorder after Alzheimer disease. Although the major...

Topics

Animals
Diagnostic Imaging
Humans
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
Mutation
Parkinson Disease
Polymorphism, Genetic
Protein Serine-Threonine Kinases
Racial Groups

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