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Article

[Research progress on the molecular genetic mechanism of Parkinson's disease].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 10 Feb 2026

Quan Wei

Abstract excerpt

The pathogenesis of Parkinson's disease is closely related to genetic factors. This article has systematically reviewed the research progress of molecular genetic mechanism on Parkinson's disease by focusing on the role of six high-penetrance pathogenic genes (SNCA, LRRK2, PRKN, PINK1, PARK7, and VPS35) and some risk genes (such as GBA1). These genetic variants eventually converge in three core pathogenic...

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Source

Identifiers

PMID: 41663306
DOI: 10.3760/cma.j.cn511374-20251021-00617

Genes

GBA1
PARK7
PINK1
PRKN
SNCA
VPS35

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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