Article
MTHFR C677T polymorphism and osteoporotic fractures.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 1 Aug 2007
Valero C, Alonso M A, Zarrabeitia M T, Viadero C, Hernández J L, Riancho J A
Abstract excerpt
The C677T (rs1801133) polymorphism of MTHFR (methylenetetrahydrofolate reductase) has been associated with the risk of cardiovascular events, and also with osteoporosis in some studies. However, the results are controversial. Our objective was to determine the relationship of the polymorphism with osteoporotic fractures by means of a case-control study. C677T was analyzed in 823 subjects (365 controls, 136 with...
Topics
- Aged
- Aged, 80 and over
- Case-Control Studies
- Female
- Fractures, Bone
- Genetic Predisposition to Disease
- Genotype
- Hip Fractures