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Article

Association of the methylenetetrahydrofolate reductase C677T polymorphism and fracture risk in Chinese postmenopausal women.

Bone - 1 Mar 2007

Hong Xiumei, Hsu Yi-Hsiang, Terwedow Henry, Tang Genfu, Liu Xue, Jiang Shanqun, Xu Xin, Xu Xiping

Abstract excerpt

Osteoporotic fractures are a leading cause of disability and, indirectly, of death in the elderly population. Previous studies have shown that homocysteine level and the C677T polymorphism in the gene encoding methylenetetrahydrofolate reductase (MTHFR) may be involved in the development of osteoporosis and its related fracture in European populations. The aim of this study was to verify the association of this...

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Source

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Identifiers

PMID: 17174622
DOI: 10.1016/j.bone.2006.09.031
PMCID: PMC1855293

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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