Article
MTHFR polymorphism and bone mineral density: meta-analysis of published studies.
Calcified tissue international - 1 Nov 2006
Riancho J A, Valero C, Zarrabeitia M T
Abstract excerpt
The C677T (rs1801133) polymorphism of methylenetetrahydrofolate reductase (MTHFR) has been associated with bone status in some studies, but the results have been mixed. In order to have a better understanding of this issue, we performed a meta-analysis of studies about the association of the C677T polymorphism and bone mineral density (BMD). Eight studies analyzed the relationship with spine BMD. When their...
Topics
- Bone Density
- Female
- Humans
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Polymorphism, Single Nucleotide