Article
Evidence for an association of methylene tetrahydrofolate reductase polymorphism C677T and an increased risk of fractures: results from a population-based Danish twin study.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Aug 2004
Bathum Lise, von Bornemann Hjelmborg Jacob, Christiansen Lene, Madsen Jonna Skov, Skytthe Axel, Christensen Kaare
Abstract excerpt
Osteoporotic fractures are some of the major causes of morbidity and health care expenditure among the elderly. Identifying subjects at risk could be of major importance since several preventive treatments are now available. A large genetic component in the development of osteoporosis has been established. Previous studies concerning association of the common point mutation C677T in methylentetrahydrofolate...
Topics
- Aged
- Denmark
- Female
- Fractures, Bone
- Genotype
- Homocysteine
- Humans
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)