Article
Correlations of SDF-1ɑ and XRCC1 gene polymorphisms with the risk of renal cancer development and bioinformatics studies of SDF-1α and XRCC1 and the prognosis of renal cancer.
Scientific reports - 9 Feb 2024
Zhang Wenjing, Su Yubo, Yue Genquan, Zhao Lingyan, Li Hailing, Jia Min, Wang Yuqi, Liu Dongyang, Wang Haisheng, Gao Yumin
Abstract excerpt
To study the relationships between stromal cell-derived factor-1 (SDF-1ɑ) and renal cell carcinoma (RCC) susceptibility and the presence of single nucleotide polymorphisms in the human X-ray cross-complementary repair gene (XRCC1). Compare SDF-1 based on RCC related data in the TCGA database α, The expression difference of XRCC1 between RCC tissue and normal tissue; Collect 166 newly diagnosed RCC cases and 166...
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