Article
Vascular endothelial growth factor gene polymorphisms and the risk of renal cell carcinoma: Evidence from eight case-control studies.
Oncotarget - 31 Jan 2017
Gong Mancheng, Dong Wenjing, Shi Zhirong, Qiu Shaopeng, Yuan Runqiang
Abstract excerpt
BACKGROUND: Vascular endothelial growth factor (VEGF) protein plays important role in renal cell carcinoma (RCC) development and progression. VEGF gene polymorphisms can alter the protein concentrations and might be associated with renal cell carcinoma risk. However, the results of studies investigating the association between VEGF polymorphisms and renal cell carcinoma risk are inconsistent. Thus, a...
Topics
- Biomarkers, Tumor
- Carcinoma, Renal Cell
- Case-Control Studies
- Chi-Square Distribution
- Genetic Association Studies
- Genetic Predisposition to Disease
- Humans
- Kidney Neoplasms
- Odds Ratio
- Phenotype
