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Article

Apolipoprotein E/C1 locus variants modify renal cell carcinoma risk.

Cancer research - 15 Oct 2009

Moore Lee E, Brennan Paul, Karami Sara, Menashe Idan, Berndt Sonja I, Dong Linda M, Meisner Allison, Yeager Meredith, Chanock Stephen, Colt Joanne, Schwartz Kendra, Davis Faith, Zaridze David, Mattveev Vsevolod, Janout Vladimir, Kollarova Hellena, Bencko Vladimir, Navratilova Marie, Szeszenia-Dabrowska Neonilia, Mates Dana, Holcatova Ivana, Boffetta Paolo, Chow Wong-Ho, Rosenberg Philip S, Rothman Nathaniel

Abstract excerpt

Lipid peroxidation is considered a unifying mechanistic pathway through which known risk factors induce renal cell carcinoma (RCC). We hypothesized that genes selected a priori for their role in lipid peroxidation would modify cancer risk. We genotyped 635 single nucleotide polymorphisms (SNP) in...

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Source

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Identifiers

PMID: 19808960
DOI: 10.1158/0008-5472.CAN-09-1734
PMCID: PMC2793179

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19808960-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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