Article
LIPC variants in the promoter and intron 1 modify HDL-C levels in a sex-specific fashion.
Atherosclerosis - 1 May 2009
Feitosa Mary F, Myers Richard H, Pankow James S, Province Michael A, Borecki Ingrid B
Abstract excerpt
We previously reported linkage for plasma levels of high-density lipoprotein cholesterol (HDL-C) on 15q21 in Caucasian families from the National Heart, Lung, and Blood Institute Family Heart Study (NHLBI FHS). Hepatic lipase gene (LIPC), which has a major role in lipoprotein metabolism, resides within the linkage region and constitutes an obvious candidate gene. While hepatic lipase is a known player in HDL...
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