Article
Polymorphisms in the hepatic lipase gene affect plasma HDL-cholesterol levels in a Turkish population.
Journal of lipid research - 1 Feb 2010
Hodoglugil Ugur, Williamson David W, Mahley Robert W
Abstract excerpt
We investigated the effects of single nucleotide polymorphisms (SNPs) of the hepatic lipase gene (LIPC) on plasma HDL-cholesterol (HDL-C) levels in Turks, a population with low levels of HDL-C. All exons and six evolutionarily conserved regions from 28 Turkish subjects were sequenced. We found 51 SNPs, nine of which were novel. Those 51 SNPs and SNPs from the National Center for Biotechnology Information dbSNP...
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