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Article

Hepatic lipase (LIPC) sequencing in individuals with extremely high and low high-density lipoprotein cholesterol levels.

PloS one - 1 Jan 2020

Pirim Dilek, Bunker Clareann H, Hokanson John E, Hamman Richard F, Demirci F Yesim, Kamboh M Ilyas

Abstract excerpt

Common variants in the hepatic lipase (LIPC) gene have been shown to be associated with plasma lipid levels; however, the distribution and functional features of rare and regulatory LIPC variants contributing to the extreme lipid phenotypes are not well known. This study was aimed to catalogue LIPC variants by resequencing the entire LIPC gene in 95 non-Hispanic Whites (NHWs) and 95 African blacks (ABs) with...

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Share to Cholesterol
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33326441
DOI: 10.1371/journal.pone.0243919
PMCID: PMC7743991

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