Article
Association of endothelial lipase gene (LIPG) haplotypes with high-density lipoprotein cholesterol subfractions and apolipoprotein AI plasma levels in Japanese Americans.
Atherosclerosis - 1 Mar 2006
Hutter Carolyn M, Austin Melissa A, Farin Federico M, Viernes Hannah-Malia, Edwards Karen L, Leonetti Donna L, McNeely Marguerite J, Fujimoto Wilfred Y
Abstract excerpt
The LIPG gene on chromosome 18 encodes for endothelial lipase, a member of the triglyceride lipase family. Mouse models suggest that variation in LIPG influences high-density lipoprotein (HDL) metabolism, but only limited data are available in humans. This study examined associations of LIPG haplotypes, comprising a single nucleotide polymorphism (SNP) in the promoter region (-384A>C), and a nonsynonymous SNP in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.