Article
Characterization of a new human apolipoprotein A-I Yame by direct sequencing of polymerase chain reaction-amplified DNA.
Journal of lipid research - 1 Aug 1991
Takada Y, Sasaki J, Seki M, Ogata S, Teranishi Y, Arakawa K
Abstract excerpt
A new genetic variant apolipoprotein (apo), A-I Yame, was discovered during screening for apoA-I genetic variants with isoelectric focusing gel electrophoresis. To investigate the structural abnormality of apoA-I Yame, we amplified the apoA-I gene isolated from the proband's peripheral blood leuk...
Topics
- Alleles
- Amino Acid Sequence
- Apolipoprotein A-I
- Apolipoproteins A
- Base Sequence
- Female
- Humans
- Immunoelectrophoresis, Two-Dimensional
- Isoelectric Focusing
- Middle Aged
- Molecular Sequence Data
- Mutagenesis
- Pedigree
- Polymerase Chain Reaction
