Article
Simple and effective determination of apolipoprotein E genotypes by positive/negative polymerase chain reaction products.
Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Sept 2006
Seripa Davide, Signori Emanuela, Gravina Carolina, Matera Maria Giovanna, Rinaldi Monica, Fazio Vito M
Abstract excerpt
Several protein and DNA-based methods have been previously described for the identification of apolipoprotein E isoforms or genotypes. However, all of them generate frequently false-positive results. The purpose of this study was to set up a new, simple, and effective method for the analysis of the apoE polymorphism. A total of 1,253 subjects previously examined for the apolipoprotein E polymorphism by...
Topics
- Adult
- Apolipoproteins E
- Cardiovascular Diseases
- DNA
- DNA Primers
- Female
- Genotype
- Heterozygote
- Humans
- Male
- Middle Aged
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Risk