Article
Synchrony dynamics during initiation, failure, and rescue of the segmentation clock.
Science (New York, N.Y.) - 28 Sept 2007
Riedel-Kruse Ingmar H, Müller Claudia, Oates Andrew C
Abstract excerpt
The "segmentation clock" is thought to coordinate sequential segmentation of the body axis in vertebrate embryos. This clock comprises a multicellular genetic network of synchronized oscillators, coupled by intercellular Delta-Notch signaling. How this synchrony is established and how its loss determines the position of segmentation defects in Delta and Notch mutants are unknown. We analyzed the clock's synchrony...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.