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Article

Hopf bifurcation in the presomitic mesoderm during the mouse segmentation.

Journal of theoretical biology - 7 Jul 2009

González Aitor, Kageyama Ryoichiro

Abstract excerpt

Vertebrae and ribs arise from embryonic tissues called somites. Somites arise sequentially from the unsegmented embryo tail, called presomitic mesoderm (PSM). The pace of somite formation is controlled by gene products such as hairy and enhancer of split 7 (Hes7) whose expression oscillates in the PSM. In addition to the cyclic genes, there is a gradient of fibroblast growth factor 8 (Fgf8) mRNA from posterior to...

Topics

Animals
Basic Helix-Loop-Helix Transcription Factors
Computer Simulation
Down-Regulation
Fibroblast Growth Factor 8
Mesoderm
Mice
Mice, Knockout
Morphogenesis
Mutation
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptor, Fibroblast Growth Factor, Type 1

Receptors, Notch

Signal Transduction

Source

Identifiers

PMID: 19236883
DOI: 10.1016/j.jtbi.2009.02.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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