Article
Lipoprotein lipase mRNA expression in whole blood is a prognostic marker in B cell chronic lymphocytic leukemia.
Clinical chemistry - 1 Feb 2007
Van Bockstaele Femke, Pede Valerie, Janssens Ann, Callewaert Filip, Offner Fritz, Verhasselt Bruno, Philippé Jan
Abstract excerpt
BACKGROUND: Chronic lymphocytic leukemia (CLL) is characterized by high individual variability in clinical course and the need for therapy. Differentiation of prognostic subgroups is based primarily on the mutation status of the genes for the variable region of the immunoglobulin heavy chain (IGHV). The time- and labor-intensive nature of this analysis necessitates the use of easily applicable surrogate markers....
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