Article
High-resolution single nucleotide polymorphism array analysis of epithelial ovarian cancer reveals numerous microdeletions and amplifications.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Aug 2007
Gorringe Kylie L, Jacobs Sharoni, Thompson Ella R, Sridhar Anita, Qiu Wen, Choong David Y H, Campbell Ian G
Abstract excerpt
PURPOSE: Genetic changes in sporadic ovarian cancer are relatively poorly characterized compared with other tumor types. We have evaluated the use of high-resolution whole genome arrays for the genetic profiling of epithelial ovarian cancer. EXPERIMENTAL DESIGN: We have evaluated 31 primary ovarian cancers and matched normal DNA for loss of heterozygosity and copy number alterations using 500 K single nucleotide...
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