Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of DNA copy number alterations in ovarian serous tumors identifies new molecular genetic changes in low-grade and high-grade carcinomas.

Cancer research - 1 May 2009

Kuo Kuan-Ting, Guan Bin, Feng Yuanjian, Mao Tsui-Lien, Chen Xu, Jinawath Natini, Wang Yue, Kurman Robert J, Shih Ie-Ming, Wang Tian-Li

Abstract excerpt

Ovarian serous carcinoma, the most common and lethal type of ovarian cancer, is thought to develop from two distinct molecular pathways. High-grade (HG) serous carcinomas contain frequent TP53 mutations, whereas low-grade (LG) carcinomas arise from serous borderline tumors (SBT) and harbor mutations in KRAS/BRAF/ERBB2 pathway. However, the molecular alterations involved in the progression from SBT to LG carcinoma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomal Instability
Share to Chromosomes, Human, Pair 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 9

Share to Cystadenocarcinoma, Serous

Share to Gene Dosage

Share to Genes, Tumor Suppressor

Share to MicroRNAs

Share to Ovarian Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 19383911
DOI: 10.1158/0008-5472.CAN-08-3913
PMCID: PMC2782554

Genes

BRAF
CSMD1
DOCK4
ERBB2
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of DNA copy number alterations in ovarian serous tumors identifies new molecular genetic changes in low-grade and high-grade carcinomas.PMID 19383911Read ↗

Amplicon profiles in ovarian serous carcinomas.Semantic proximity Read ↗

The Changing View of High-Grade Serous Ovarian CancerSemantic proximity Read ↗

Genome Wide DNA Copy Number Analysis of Serous Type Ovarian Carcinomas Identifies Genetic Markers Predictive of Clinical OutcomeSemantic proximity Read ↗

Critical molecular abnormalities in high-grade serous carcinoma of the ovary.Semantic proximity Read ↗

Genomic Analyses of Germline and Somatic Variation in High-Grade Serous Ovarian CancerSemantic proximity Read ↗

Genetic and molecular changes in ovarian cancerSemantic proximity Read ↗

Genomic analyses of germline and somatic variation in high-grade serous ovarian cancerSemantic proximity Read ↗

Histologic, molecular, and cytogenetic features of ovarian cancers: implications for diagnosis and treatment.Semantic proximity Read ↗

High-Grade Serous Ovarian Carcinoma in the Genomics Era: Current Applications, Challenges and Future Directions.Semantic proximity Read ↗

Comprehensive Genomic Characterization in Ovarian Low-Grade and Chemosensitive and Chemoresistant High-Grade Serous Carcinomas.Semantic proximity Read ↗

DNA copy numbers profiles in affinity-purified ovarian clear cell carcinoma.Semantic proximity Read ↗

Single-Cell Dissection of the Multiomic Landscape of High-Grade Serous Ovarian CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.