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Article

Patterns of somatically acquired amplifications and deletions in apparently normal tissues of ovarian cancer patients.

Cell reports - 22 May 2014

Aghili Leila, Foo Jasmine, DeGregori James, De Subhajyoti

Abstract excerpt

Little is understood about the occurrence of somatic genomic alterations in normal tissues and their significance in the context of disease. Here, we identified potential somatic copy number alterations (pSCNAs) in apparently normal ovarian tissue and peripheral blood of 423 ovarian cancer patients. There were, on average, two to four pSCNAs per sample detectable at a tissue-level resolution, although some...

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Identifiers

PMID: 24794429
DOI: 10.1016/j.celrep.2014.03.071
PMCID: PMC4108616

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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