Article
Identification of a characteristic copy number alteration profile by high-resolution single nucleotide polymorphism arrays associated with metastatic sporadic colorectal cancer.
Cancer - 1 Jul 2014
González-González María, Fontanillo Celia, Abad María M, Gutiérrez María L, Mota Ines, Bengoechea Oscar, Santos-Briz Ángel, Blanco Oscar, Fonseca Emilio, Ciudad Juana, Fuentes Manuel, De Las Rivas Javier, Alcazar José A, García Jacinto, Muñoz-Bellvis Luís, Orfao Alberto, Sayagués José M
Abstract excerpt
BACKGROUND: Metastatic dissemination is the most frequent cause of death in patients with sporadic colorectal cancer (sCRC). It is believed that the metastatic process is related at least in part to a specific background of genetic alterations accumulated in cells from primary tumors, and the abi...
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