Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of novel copy number variants in uterine leiomyomas using high-resolution SNP arrays.

Molecular human reproduction - 1 Sept 2009

Bowden Wayne, Skorupski Josh, Kovanci Ertug, Rajkovic Aleksandar

Abstract excerpt

Uterine leiomyomas (ULs) are benign monoclonal tumors originating from myometrial tissue in the uterus. Genetic pathways that lead to myometrial transformation into leiomyomas are largely unknown. Approximately 40% of ULs are karyotypically abnormal by G-banding; however, the remaining 60% of leiomyomas do not contain cytogenetically visible genomic rearrangements. Recent technological advances such as array...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Gene Dosage
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leiomyoma

Share to Oligonucleotide Array Sequence Analysis

Share to Polymerase Chain Reaction

Share to Polymorphism, Single Nucleotide

Share to Uterine Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 19567454
DOI: 10.1093/molehr/gap050
PMCID: PMC2725754

Genes

RHOU
WASF3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of novel copy number variants in uterine leiomyomas using high-resolution SNP arrays.PMID 19567454Read ↗

Large-scale analysis of chromosomal aberrations in uterine leiomyoma.Semantic proximity Read ↗

Characterization of uterine leiomyomas by whole-genome sequencing.Semantic proximity Read ↗

Genome-wide analysis of loss of heterozygosity and copy number amplification in uterine leiomyomas using the 100K single nucleotide polymorphism array.Semantic proximity Read ↗

Genomic Insights into Uterine Leiomyomas: A Systematic Review of Whole-Genome and Whole- Exome Sequencing StudiesSemantic proximity Read ↗

Chromosomal and gene mapping of uterine fibroids: A systematic review.Semantic proximity Read ↗

Highly heterogeneous genomic landscape of uterine leiomyomas by whole exome sequencing and genome-wide arrays.Semantic proximity Read ↗

3'RNA and whole-genome sequencing of archival uterine leiomyomas reveal a tumor subtype with chromosomal rearrangements affecting either HMGA2, HMGA1, or PLAG1.Semantic proximity Read ↗

Molecular differential diagnosis of uterine leiomyomas and leiomyosarcomas.Semantic proximity Read ↗

Integrated data analysis reveals uterine leiomyoma subtypes with distinct driver pathways and biomarkers.Semantic proximity Read ↗

Integrative Genomic and Transcriptomic Profiling Reveals a Differential Molecular Signature in Uterine Leiomyoma versus LeiomyosarcomaSemantic proximity Read ↗

Integrative analysis of uterine leiomyoma genetics, epigenomics, and single-cell transcriptomics reveals causal genetic variants, gene targets, and cell typesSemantic proximity Read ↗

Microallelotyping defines novel regions of loss of heterozygosity in uterine leiomyomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.