Article
Association between allelic polymorphisms of metabolizing enzymes (CYP 1A1, CYP 1A2, CYP 2E1, mEH) and occurrence of colorectal cancer in Hungary.
Anticancer research - 1 Jan 2000
Kiss István, Orsós Zsuzsa, Gombos Katalin, Bogner Barna, Csejtei András, Tibold Antal, Varga Zsuzsa, Pázsit Emese, Magda Ingrid, Zölyomi Annamária, Ember István
Abstract excerpt
BACKGROUND: Genetic polymorphisms of metabolizing enzymes may affect the risk of cancer formation in humans. Since the diet can contain polycyclic aromatic hydrocarbons (PAHs) and heterocyclic amines (HAs), the relationship between polymorphisms of enzymes involved in PAH and HA metabolism and the occurrence of sporadic colorectal cancer was studied. PATIENTS AND METHODS: Five hundred colorectal cancer patients...
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