Article
Colorectal cancer risk in relation to genetic polymorphism of cytochrome P450 1A1, 2E1, and glutathione-S-transferase M1 enzymes.
Anticancer research - 1 Jan 2000
Kiss I, Sándor J, Pajkos G, Bogner B, Hegedüs G, Ember I
Abstract excerpt
Chemical carcinogens generally require metabolic activation in order to be able to bind to DNA and contribute to cancer causation. Most of the human metabolizing enzymes are genetically polymorphic, and these polymorphisms may affect the enzyme activity or inducibility. In our present study we in...
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