Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in xenobiotic metabolizing enzymes and diet influence colorectal adenoma risk.

Pharmacogenetics and genomics - 1 May 2010

Northwood Emma L, Elliott Faye, Forman David, Barrett Jennifer H, Wilkie Murray J V, Carey Francis A, Steele Robert J C, Wolf Roland, Bishop Timothy, Smith Gillian

Abstract excerpt

OBJECTIVES: We have earlier shown that diet and xenobiotic metabolizing enzyme genotypes influence colorectal cancer risk, and now investigate whether similar associations are seen in patients with premalignant colorectal adenomas (CRA), recruited during the pilot phase of the Scottish Bowel Screening Programme. METHODS: Nineteen polymorphisms in 13 genes [cytochrome P450 (P450), glutathione S-transferase (GST),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetyltransferases
Share to Adenoma

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epoxide Hydrolases

Share to Glutathione Transferase

Share to NAD(P)H Dehydrogenase (Quinone)

Share to Surveys and Questionnaires

Share to Xenobiotics

Source

Identifiers

PMID: 20375710
DOI: 10.1097/FPC.0b013e3283395c6a

Genes

EPHX1
GSTM1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in xenobiotic metabolizing enzymes and diet influence colorectal adenoma risk.PMID 20375710Read ↗

A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer.Semantic proximity Read ↗

A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer.Semantic proximity Read ↗

Role of NQO1C609T and EPHX1 gene polymorphisms in the association of smoking and alcohol with sporadic distal colorectal adenomas: results from the UKFSS Study.Semantic proximity Read ↗

Role of epoxide hydrolase, NAD(P)H:quinone oxidoreductase, cytochrome P450 2E1 or alcohol dehydrogenase genotypes in susceptibility to colorectal cancer.Semantic proximity Read ↗

Association between exposure-relevant polymorphisms in CYP1B1, EPHX1, NQO1, GSTM1, GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population.Semantic proximity Read ↗

Vegetable, fruit and meat consumption and potential risk modifying genes in relation to colorectal cancer.Semantic proximity Read ↗

Cytochrome P450 1A1, 2E1 and GSTM1 gene polymorphisms and susceptibility to colorectal cancer in the Saudi population.Semantic proximity Read ↗

CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms.Semantic proximity Read ↗

Interactions between cigarette smoking and selected polymorphisms in xenobiotic metabolizing enzymes in risk for colorectal cancer: A case-only analysis.Semantic proximity Read ↗

Metabolic genotypes and risk for colorectal cancer.Semantic proximity Read ↗

Polymorphisms in the xenobiotic transporter Multidrug Resistance 1 (MDR1) and interaction with meat intake in relation to risk of colorectal cancer in a Danish prospective case-cohort study.Semantic proximity Read ↗

The Effect of the CYP1A1*2A Allele on Colorectal Cancer Susceptibility in a British Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.