Article
Association between exposure-relevant polymorphisms in CYP1B1, EPHX1, NQO1, GSTM1, GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population.
Oncology reports - 1 Nov 2010
Hlavata Ivona, Vrana David, Smerhovsky Zdenek, Pardini Barbara, Naccarati Alessio, Vodicka Pavel, Novotny Jan, Mohelnikova-Duchonova Beatrice, Soucek Pavel
Abstract excerpt
Associations of functional single nucleotide polymorphisms in cytochrome P450 1B1, epoxide hydrolase 1, NAD(P)H:quinone oxidoreductase 1, glutathione S-transferase Pi-1 and deletions of glutathione S-transferases Mu-1 and θ-1 with colorectal cancer risk were investigated in a hospital-based case-control study on 495 matched pairs of Czech Caucasians. Polymorphisms were assessed by polymerase chain reaction...
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