Article
CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms.
World journal of gastroenterology - 7 Dec 2016
Fernandes Glaucia Maria M, Russo Anelise, Proença Marcela Alcântara, Gazola Nathalia Fernanda, Rodrigues Gabriela Helena, Biselli-Chicote Patrícia Matos, Silva Ana Elizabete, Netinho João Gomes, Pavarino Érika Cristina, Goloni-Bertollo Eny Maria
Abstract excerpt
AIM: To investigate the contribution of polymorphisms in the CYP1A1, CYP2E1 and EPHX1 genes on sporadic colorectal cancer (SCRC) risk. METHODS: Six hundred forty-one individuals (227 patients with SCRC and 400 controls) were enrolled in the study. The variables analyzed were age, gender, tobacco and alcohol consumption, and clinical and histopathological tumor parameters. The CYP1A1*2A, CYP1A1*2C CYP2E1*5B and...
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