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Article

GnRH and LHR gene variants predict adverse outcome in premenopausal breast cancer patients.

Breast cancer research : BCR - 1 Jan 2007

Piersma Djura, Themmen Axel P N, Look Maxime P, Klijn Jan G M, Foekens John A, Uitterlinden André G, Pols Huibert A P, Berns Els M J J

Abstract excerpt

BACKGROUND: Breast cancer development and progression are dependent on estrogen activity. In premenopausal women, estrogen production is mainly regulated through the hypothalamic-pituitary-gonadal (HPG) axis. METHODS: We have investigated the prognostic significance of two variants of genes invol...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17692113
DOI: 10.1186/bcr1756
PMCID: PMC2206727

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17692113-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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