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Article

Single nucleotide polymorphisms in the regulatory region of gonadotropin-releasing hormone receptor gene and breast cancer susceptibility.

Oncology reports - 1 Sept 2012

Lattrich Claus, Müller Anna-Kristin, Schüler Susanne, Häring Julia, Ruoff Alexandra, Treeck Oliver, Ortmann Olaf

Abstract excerpt

It is known that exposure to estrogens affects the pathophysiology of breast cancer. The key role of gonadotropin-releasing hormone (GnRH) in the regulation of female steroid hormone metabolism raises the question of whether polymorphisms in its receptor, GnRHR, might influence breast cancer risk. To test this hypothesis, we analyzed three single nucleotide...

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PMID: 22710726
DOI: 10.3892/or.2012.1854

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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