Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epidermal growth factor receptor gene polymorphisms are associated with prognostic features of breast cancer.

BMC cancer - 14 Mar 2014

Leite Marcelo Sobral, Giacomin Letícia Carlos, Piranda Diogo Nascimento, Festa-Vasconcellos Juliana Simões, Indio-do-Brasil Vanessa, Koifman Sérgio, de Moura-Neto Rodrigo Soares, de Carvalho Marcelo Alex, Vianna-Jorge Rosane

Abstract excerpt

BACKGROUND: The epidermal growth factor receptor (EGFR) is differently expressed in breast cancer, and its presence may favor cancer progression. We hypothesized that two EGFR functional polymorphisms, a (CA)n repeat in intron 1, and a single nucleotide polymorphism, R497K, may affect EGFR expression and breast cancer clinical profile. METHODS: The study population consisted of 508 Brazilian women with unilateral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brazil

Share to Breast Neoplasms

Share to Cohort Studies

Share to ErbB Receptors

Share to Polymorphism, Genetic

Share to Prognosis

Source

Open in PubMed Open full text

Identifiers

PMID: 24629097
DOI: 10.1186/1471-2407-14-190
PMCID: PMC3995591

Genes

EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epidermal growth factor receptor gene polymorphisms are associated with prognostic features of breast cancer.PMID 24629097Read ↗

Evaluation of the EGFR polymorphism R497K in two cohorts of neoadjuvantly treated breast cancer patients.Semantic proximity Read ↗

Lack of evidence for prognostic value of epidermal growth factor receptor intron-1 CA repeats for oral carcinomas.Semantic proximity Read ↗

Association between the length of a CA dinucleotide repeat in the EGFR and risk of breast cancer.Semantic proximity Read ↗

HER1 R497K and HER2 I655V polymorphisms are linked to development of breast cancer.Semantic proximity Read ↗

EGFR Intron 1 polymorphism in Asian Populations and its correlation with EGFR gene expression and amplification in breast tumor tissues.Semantic proximity Read ↗

ERBB4 promoter polymorphism is associated with poor distant disease-free survival in high-risk early breast cancer.Semantic proximity Read ↗

High prevalence of EGFR R479K (rs2227983) polymorphism in Indian Head and Neck Cancer Patients: Association with Unfavourable Clinical OutcomeSemantic proximity Read ↗

Modification of Breast Cancer Risk in Young Women by a Polymorphic Sequence in the egfr GeneSemantic proximity Read ↗

Interleukin 7 receptor alpha Thr244Ile genetic polymorphism is associated with susceptibility and prognostic markers in breast cancer subgroups.Semantic proximity Read ↗

Microsatellite profile in hormonal receptor genes associated with breast cancer.Semantic proximity Read ↗

A common and functional gene variant in the vascular endothelial growth factor a predicts clinical outcome in early-stage breast cancer.Semantic proximity Read ↗

The EGFR R521K polymorphism influences the risk to develop colorectal cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.