Genetic polymorphisms of the GNRH1 and GNRHR genes and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3).

doi:10.1186/1471-2407-9-257

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Genetic polymorphisms of the GNRH1 and GNRHR genes and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3).

BMC cancer - 29 Jul 2009

Canzian Federico, Kaaks Rudolf, Cox David G, Henderson Katherine D, Henderson Brian E, Berg Christine, Bingham Sheila, Boeing Heiner, Buring Julie, Calle Eugenia E, Chanock Stephen, Clavel-Chapelon Francoise, Dossus Laure, Feigelson Heather Spencer, Haiman Christopher A, Hankinson Susan E, Hoover Robert, Hunter David J, Isaacs Claudine, Lenner Per, Lund Eiliv, Overvad Kim, Palli Domenico, Pearce Celeste Leigh, Quiros Jose R, Riboli Elio, Stram Daniel O, Thomas Gilles, Thun Michael J, Trichopoulos Dimitrios, van Gils Carla H, Ziegler Regina G

Abstract excerpt

BACKGROUND: Gonadotropin releasing hormone (GNRH1) triggers the release of follicle stimulating hormone and luteinizing hormone from the pituitary. Genetic variants in the gene encoding GNRH1 or its receptor may influence breast cancer risk by modulating production of ovarian steroid hormones. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Exons

Share to Gonadotropin-Releasing Hormone

Share to Neoplasm Invasiveness

Share to Protein Precursors

Share to Receptors, LHRH

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 19640273
DOI: 10.1186/1471-2407-9-257
PMCID: PMC2729775

Genes

GNRH1
GNRHR
NHS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19640273-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms of the GNRH1 and GNRHR genes and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3).PMID 19640273Read ↗

Single nucleotide polymorphisms in the regulatory region of gonadotropin-releasing hormone receptor gene and breast cancer susceptibility.Semantic proximity Read ↗

Genetic variation at the CYP19A1 locus predicts circulating estrogen levels but not breast cancer risk in postmenopausal women.Semantic proximity Read ↗

GnRH and LHR gene variants predict adverse outcome in premenopausal breast cancer patients.Semantic proximity Read ↗

Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium.Semantic proximity Read ↗

CYP19A1 genetic variation in relation to prostate cancer risk and circulating sex hormone concentrations in men from the Breast and Prostate Cancer Cohort Consortium.Semantic proximity Read ↗

A comprehensive analysis of the androgen receptor gene and risk of breast cancer: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3).Semantic proximity Read ↗

Genetic variation in estrogen and progesterone pathway genes and breast cancer risk: an exploration of tumor subtype-specific effects.Semantic proximity Read ↗

HSD17B1 genetic variants and hormone receptor-defined breast cancer.Semantic proximity Read ↗

The nucleotide sequences of human GnRH receptors in breast and ovarian tumors are identical with that found in pituitarySemantic proximity Read ↗

Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study.Semantic proximity Read ↗

CYP17 genetic variation and risk of breast and prostate cancer from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3).Semantic proximity Read ↗

Common genetic variation in IGF1, IGFBP1 and IGFBP3 and ovarian cancer risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.