Article
Polymorphic variations in exon 10 of the luteinizing hormone receptor: functional consequences and associations with breast cancer.
Molecular and cellular endocrinology - 30 Sept 2007
Piersma Djura, Verhoef-Post Miriam, Look Maxime P, Uitterlinden André G, Pols Huibert A P, Berns Els M J J, Themmen Axel P N
Abstract excerpt
Polymorphic variation of the LHR gene may affect receptor function and accordingly may influence ovarian steroid hormone action, including steroid hormone-dependent clinical outcome. The functional effects of two single nucleotide polymorphisms (SNPs), i.e. LHR 291Asn/Ser (rs12470652) and 312Ser/...
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