Article
Whole-genome amplification of oral rinse self-collected DNA in a population-based case-control study of breast cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2007
Liang Xueying, Trentham-Dietz Amy, Titus-Ernstoff Linda, Newcomb Polly A, Welch Rober A, Hutchinson Amy A, Hampton John M, Sutcliffe Cara B, Haines Jonathan L, Egan Kathleen M
Abstract excerpt
The availability of large amounts of genomic DNA (gDNA) is the limiting factor for many of the molecular biology assays in genetic epidemiologic studies. Whole-genome amplification using multiple displacement amplification is used to amplify a representative sample of gDNA from small amounts of gDNA to optimize gDNA yield. We collected oral rinse DNA samples through the mail from 3,377 women enrolled in a...
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