Article
Assessment of multiple displacement amplification in molecular epidemiology.
BioTechniques - 1 Jul 2004
Yan Jin, Feng Jinong, Hosono Seiyu, Sommer Steve S
Abstract excerpt
Well-characterized epidemiological resources are generated with great effort, yet associated patient DNA samples can be limiting. The efficacy of the whole genome amplification (WGA) method, termed multiple displacement amplification (MDA), was assessed for detecting heterozygous sequence variants, mutation scanning, and PCR for challenging segments. Fifteen common polymorphisms from 10 genes located on 8...
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