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Article

Comprehensive human genome amplification using multiple displacement amplification.

Proceedings of the National Academy of Sciences of the United States of America - 16 Apr 2002

Dean Frank B, Hosono Seiyu, Fang Linhua, Wu Xiaohong, Faruqi A Fawad, Bray-Ward Patricia, Sun Zhenyu, Zong Qiuling, Du Yuefen, Du Jing, Driscoll Mark, Song Wanmin, Kingsmore Stephen F, Egholm Michael, Lasken Roger S

Abstract excerpt

Fundamental to most genetic analysis is availability of genomic DNA of adequate quality and quantity. Because DNA yield from human samples is frequently limiting, much effort has been invested in developing methods for whole genome amplification (WGA) by random or degenerate oligonucleotide-primed PCR. However, existing WGA methods like degenerate oligonucleotide-primed PCR suffer from incomplete coverage and...

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Identifiers

PMID: 11959976
DOI: 10.1073/pnas.082089499
PMCID: PMC122757

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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