Article
Multiple displacement amplification prior to single nucleotide polymorphism genotyping in epidemiologic studies.
Biotechnology letters - 1 Jul 2003
Tranah Gregory J, Lescault Pamela J, Hunter David J, De Vivo Immaculata
Abstract excerpt
We assessed the whole genome amplification strategy, known as multiple displacement amplification (MDA), for use with the TaqMan genotyping platform for DNA samples derived from two case-control studies nested in the Nurses' Health Study and the Physicians' Health Study. Our objectives were to (1) quantify DNA yield from samples of varying starting concentrations and (2) assess whether MDA products give an...
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