gamma(c) cytokines provide multiple homeostatic signals to naive CD4(+) T cells.

Abstract excerpt

Cytokines signaling through receptors sharing the common gamma chain (gamma(c)), including IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21, are critical for the generation and peripheral homeostasis of B, T and NK cells. To identify unique or redundant roles for gamma(c) cytokines in naive CD4(+) T cells, we compared monoclonal populations of CD4(+) T cells from TCR-Tg mice that were gamma(c) (+), gamma(c) (-),...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to CD4-Positive T-Lymphocytes
• Share to Cell Size