Article
Vessel and blood specification override cardiac potential in anterior mesoderm.
Developmental cell - 1 Aug 2007
Schoenebeck Jeffrey J, Keegan Brian R, Yelon Deborah
Abstract excerpt
Organ progenitors arise within organ fields, embryonic territories that are larger than the regions required for organ formation. Little is known about the regulatory pathways that define organ field boundaries and thereby limit organ size. Here we identify a mechanism for restricting heart size through confinement of the developmental potential of the heart field. Via fate mapping in zebrafish, we locate cardiac...
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