BOP, a regulator of right ventricular heart development, is a direct transcriptional target of MEF2C in the developing heart

doi:10.1242/dev.01849

Article

BOP, a regulator of right ventricular heart development, is a direct transcriptional target of MEF2C in the developing heart

12 May 2005

Abstract excerpt

The vertebrate heart is assembled during embryogenesis in a modular manner from different populations of precursor cells. The right ventricular chamber and outflow tract are derived primarily from a population of progenitors known as the anterior heart field. These regions of the heart are severely hypoplastic in mutant mice lacking the myocyte enhancer factor 2C (MEF2C) and BOP transcription factors, suggesting...

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