Article
L-ficolin (ficolin-2) insufficiency is associated with combined allergic and infectious respiratory disease in children.
Molecular immunology - 1 Dec 2009
Cedzynski Maciej, Atkinson Anne P M, St Swierzko Anna, MacDonald Shirley L, Szala Agnieszka, Zeman Krzysztof, Buczylko Krzysztof, Bak-Romaniszyn Leokadia, Wiszniewska Magdalena, Matsushita Misao, Szemraj Janusz, Banasik Małgorzata, Turner Marc L, Kilpatrick David C
Abstract excerpt
We previously reported an association between relative L-ficolin deficiency and recurrent respiratory infections co-existing with allergic disorders in children. To confirm and extend this preliminary finding, we performed a prospective study on children of a similar age (mean 8.9 years) designed to establish whether the principal relationship was with infection or allergy. Serum L-ficolin values in healthy...
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