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Article

Role of osteoblast-fibroblast interactions in the formation of the ligament-to-bone interface.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Dec 2007

Wang I-Ning E, Shan Jing, Choi Rene, Oh Seongcheol, Kepler Christopher K, Chen Faye H, Lu Helen H

Abstract excerpt

The anterior cruciate ligament (ACL) inserts into bone through a characteristic fibrocartilagenous interface, which is essential for load transfer between soft and hard tissues. This multi-tissue interface is lost post ACL reconstruction, and the lack of an anatomic fibrocartilage interface between graft and bone remains the leading cause of graft failure. Currently, the mechanism of interface formation is not...

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PMID: 17676622
DOI: 10.1002/jor.20475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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