Article
Induction of ectopic bone formation by using human periosteal cells in combination with a novel scaffold technology.
Cell transplantation - 1 Jan 2002
Schantz Jan-Thorsten, Hutmacher Dietmar Werner, Chim Harvey, Ng Kee Woei, Lim Thiam Chye, Teoh Swee Hin
Abstract excerpt
Due to their osteogenic germination potential, periosteum-derived osteoprogenitor cells are a potential source for tissue engineering a bone graft that could be used to regenerate skeletal defects. In this study we evaluated if ectopic bone formation could be induced by a construct made of human periosteal cells and a novel scaffold architecture whose mechanical properties are in the range of cancellous bone....
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