Article
Composite scaffolds: bridging nanofiber and microsphere architectures to improve bioactivity of mechanically competent constructs.
Journal of biomedical materials research. Part A - 15 Dec 2010
Brown Justin L, Peach M Sean, Nair Lakshmi S, Kumbar Sangamesh G, Laurencin Cato T
Abstract excerpt
Tissue engineering often benefits from the use of composites to produce an ideal scaffold. We present the focused development of a novel structure that combines the biomimetic properties of nanofibers with the robust mechanical aspects of the sintered microsphere scaffold to produce a composite scaffold that demonstrates an ability to mimic the mechanical environment of trabecular bone while also promoting the...
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