Article
In vitro bone formation using muscle-derived cells: a new paradigm for bone tissue engineering using polymer-bone morphogenetic protein matrices.
Biochemical and biophysical research communications - 13 Jun 2003
Lu Helen H, Kofron Michelle D, El-Amin Saadiq F, Attawia Mohammed A, Laurencin Cato T
Abstract excerpt
Over 800,000 bone grafting procedures are performed in the United States annually, creating a demand for viable alternatives to autogenous bone, the grafting standard in osseous repair. The objective of this study was to examine the efficacy of a BMP-polymer matrix in inducing the expression of the osteoblastic phenotype and in vitro bone formation by muscle-derived cells. Specifically, we evaluated the ability...
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